Watch My Sister's Keeper

Conceived by means of in vitro fertilization, Anna Fitzgerald (Abigail Breslin) was brought into the world as a savior sister at the informal suggestion of Kate's doctor, Dr. Chance (David Thornton) (a formal suggestion from the doctor would have been a violation of legal and medical ethics). Anna is conceived to be a genetic match for her older sister, Kate (Sofia Vassilieva), who suffers from acute promyelocytic leukemia, to donate compatible organs, blood and tissue in order to keep her sister alive. Her family members are introduced one by one, and each tells about how Kate's illness has affected them personally. When Kate turns 15, she goes into renal failure. Eleven-year-old Anna knows that she will be forced by her parents to donate one of her kidneys. She also realizes that she may not be able to live the life she will want to lead - she may be unable to cheerlead, play soccer, or be a mother. Anna tells her parents that she does not want any of this and proceeds to sue them for medical emancipation and the rights to her own body. Her extremely overprotective mother, Sara (Cameron Diaz), who leads an obsessive campaign to keep Kate alive, is indignant at Anna's decision and even strikes her across the face when she receives the notice of court proceedings. Attorney Campbell Alexander (Alec Baldwin) agrees to work for Anna as her guardian ad litem, suing for partial termination of parental rights. It is later learned he agreed to take the case not for the notoriety but because he has epilepsy and understands her predicament of not having control over her own body. The film is interlaced with flashbacks that detail Kate and Anna's closeness, as well as how Kate's illness has affected her siblings' lives and their relationships. In a flashback, Kate also meets a fellow cancer patient, Taylor Ambrose (Thomas Dekker), whom she begins dating. After a date, they kiss outside Kate's house, with Anna and Kate's father Brian (Jason Patric) watching from their bedroom window. After this, he becomes her boyfriend in and out of hospital and supports her as she undergoes treatment. He then asks her to the hospital's "prom" for teen patients; there, they slow-dance, then proceed to a vacant hospital room to have sex. A few days later, Kate is crying because Taylor hasn't called her for several days. Her mother Sara is furious when Kate mentions they did "stuff" after the prom and storms out to ask the nurse where Taylor is, evidently believing that he had dated her daughter merely to sleep with her, and learns that he has died. Kate makes a request to go to the beach one last time, and Brian obtains permission, and compassionate encouragement, from Dr. Chance to do so. Brian removes her from the hospital for the day and takes her and the kids to the beach, encountering an overprotective-as-ever Sara at a brief stop at their house who is furious when Brian shows up with Kate and demands that she be returned to the hospital. Brian angrily refuses and drives off, threatening Sara with a divorce if she does not join them. Sara later shows up at the beach, where they enjoy one final family outing. To Sara's dismay, the judge (Joan Cusack) refuses to grant summary dismissal, and the case goes to a hearing. During the hearing, Anna and Kate's older brother, Jesse, reveal that Anna's actions are actually under Kate's instruction; Kate, not wanting to live any longer, and knowing Sara refuses to hear any option other than her desired one to keep her alive, had gently persuaded Anna to refuse to donate her kidney------it is also revealed that Anna, due to her own reluctance to see Kate die, had initially been quite upset at Kate's decision. Sara is indignant at this discovery but is finally forced by both Jesse and Brian to realize that Kate had been trying to tell her this for some time. Before the case is decided, Kate dies while sleeping at the hospital with her mother by her side. After Kate's death, Campbell brings the court decision: Anna won the case. The family moves on with their lives, but every year on Kate's birthday they go to Montana, which was her "most favorite place in the world". At the end, Anna says that she will see Kate again and that, in the meantime, their relationship continues.